Tuesday, December 11, 2012

MyPerfectGift.com Teams up with Popular Satellite Radio Host ...

by wolverine on December 11, 2012

A sz?kelykereszt?ri OKTETT zenekar, 2008-ban alakult 8 tehets?ges zen?szb?l.A zenekar ?fiatal kora? ellen?re m?r t?bb sikeres fell?p?st tud maga m?g?tt, mi t?bb a helyi VOX FM r?di? tehet?sgkutat? verseny?nek els? dij?t is elh?ditott?k a feln?tt kateg?ri?ban!A zenekar szivesen v?llal fell?p?seket c?grendezv?nyeken,?nnepi rendezv?nyeken,falu/v?rosnapokon,pubokban,k?v?z?kban,ki?llit?sokon vagy ak?r egyh?zi ?nnepek alkalm?val templomokban.Kb. 1 ?r?s reperto?rjukban megtal?lhat? a jazz-es elemekt?l,indul?kt?l,?r?kz?ldekt?l az egyh?zi spiritu?l?kig szinte b?rmi.A zenekar el?rhet? a bemutat?ban felt?ntetett telefonsz?mokon! J? sz?rakoz?st kiv?n az OKTETT zenekar Sz?kelykereszt?r e-mail:krisancsaba@netter.ro vagy sjoco@hrline.ro For English Today it houses the OKTETT orchestra, founded in 2008 in 8-musicians.A talented band of young age, despite successful action can have more behind it, what?s more local competition VOX FM radio also gained first prize in the adult category! The band pleased to take actions firms festivals, festive events, village / city days, pubs, cafes, exhibitions or religious holidays catedrals. Kb. 1 hour repertoire can be found in the jazz elements, marches, evergreens church spiritually nearly everyone.A band numbers shown in the presentation is available! Have a excellent time to the OKTETT band Cristuru Secuiesc E-mail: krisancsaba@netter.ro or sjoco@hrline.ro


Napa California (PRWEB) November 15, 2012

Amusing, vivacious radio star Taylor Strecker has made a MyPerfectGift Celebrity Registry in support of Operation Smile.

Taylor Strecker, host of a well loved morning show on Satellite Radio since 2006, is a native Bostonian and describes herself as a non-stop chatter box since coming out of the womb. The Ithaca College School of Communications grad has won over the masses with her outspoken humor and addictive personality. Nicknamed the lil shot of espresso, Taylor isnt worried to shout out what other women are thinking

Source: http://holidays.only-the-news.com/myperfectgift-com-teams-up-with-popular-satellite-radio-host-taylor-strecker-in-support-of-operation-smile/

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Monday, December 10, 2012

Fantastic Four Reboot Set for March 6, 2015

the-fantastic-four-reboot

If all goes according to plan, 2015 will be one ridiculous year for movies.? Currently, The Avengers 2, Justice League, Ant-Man, Star Wars: Episode VII, and The Hunger Games: Mockingjay Part 2 are all tentatively slated for 2015 release dates.? Now Fox is throwing one more highly anticipated title into the pile, as their Fantastic Four reboot now has a March 6, 2015 release date.? Titled The Fantastic Four, the film has Chronicle director Josh Trank at the helm and Jeremy Slater penning the screenplay.? Plot details are practically non-existent at the moment, but with two promising gents creatively spearheading the project, there?s certainly hope for a fun take on the comic book property that will help us all put?Tim Story?s overly cheesy films out of our memory for good.

Additionally, Fox has announced that a number of their upcoming films will be post-converted to 3D.? Hit the jump for more.

x-men-days-of-future-pastThe folks over at Exhibitor Relations Tweeted that Fox?s The Wolverine, X-Men: Days of Future Past, Dawn of the Planet of the Apes, and Percy Jackson: Sea of Monsters will all be released in 3D.? There?s no mention of Fantastic Four being 3D, but I imagine it will be presented in three-dimensions as well when all is said and done.? Seeing as how production on The Wolverine and Percy Jackson has already wrapped, we know that those two will be post-converted.? There?s no word on whether the other two will be shot in 3D or post-converted, but Ian McKellen recently speculated that director Bryan Singer might shoot the X-Men sequel in 3D and at 48 frames-per-second.

There has been no firm word from anyone else that Singer might go that route, and McKellen only just entered negotiations to join the project so he?s not exactly an expert on all things Days of Future Past. ?That said, Singer recently Tweeted quite a bit on a pre-production trip to New Zealand where he hung out with The Hobbit director/48 fps cheerleader Peter Jackson, so it?s certainly possible that he might be going the High Frame Rate route.? It?s also possible that he was just meeting with the people at Jackson?s visual effects studio Weta for the film, so let?s hold off on the instant backlash until we have more information.

Here?s a rundown of the release dates for Fox?s upcoming films:

the-fantastic-four

Source: http://www.rottentomatoes.com/m/1926432/news/1926432/

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Private company to offer rides to moon by 2020

Golden Spike says it hopes to sell missions to the moon for over $1 billion.

By Clara Moskowitz,?SPACE.com / December 7, 2012

This undated image made available by NASA and photographed by the Expedition 28 crew aboard the International Space Station, shows the moon, at center with the limb of Earth near the bottom transitioning into the orange-colored troposphere, the lowest and most dense portion of the Earth's atmosphere.

NASA/AP

Enlarge

A new private venture aims to sell manned trips to the moon by 2020, its founders announced today (Dec. 6).

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The company, called Golden Spike (after the final spike built into the First Transcontinental Railroad), plans to sell each moon mission for about $1.5 billion ? a relative bargain, said the company's president and CEO Alan Stern, a former director of NASA?s Science Mission Directorate.

For the same price as many unmanned robotic missions, Golden Spike will provide a round trip for two humans to the moon.

"We're selling to nations, corporations and individuals," Stern told SPACE.com. "Get in line ? and I think it's going to be a long one." [How Golden Spike's Moon Landing Plan Works (Infographic )]

Stern and Golden Spike's chairman of the board of directors, Gerry Griffin, a former Apollo flight director and NASA Johnson Space Center director, announced their plans today at the National Press Club in Washington, D.C.

Shopping for a rocket

The company's leaders have not yet chosen a launch vehicle or space capsule to transport their passengers; Stern expects to make the final selections in 2014.

To keep costs low, Golden Spike will likely use existing or already-under-development rockets and spacecraft. However, the company will need to commission its own lunar lander and specially designed spacesuits. Stern called rumors that Golden Spike had already chosen SpaceX's Falcon 9 Heavy rocket "not true."

The company has been in the works, and under wraps, for two and a half years, Stern said.

"I don?t think anybody's got us beat," he added. "This is state-of-the-art cool."

The missions are being targeted at countries without their own space agencies or that can't afford to launch people to the moon independently, as well as scientific organizations and even private individuals looking to take the trip of a lifetime.

"We have spoken to space agencies from both Asian and European countries and found real interest," Stern said.

Private moon race

Source: http://rss.csmonitor.com/~r/feeds/science/~3/UbH0hPTO37Q/Private-company-to-offer-rides-to-moon-by-2020

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Sunday, December 9, 2012

Businesses Urged To Get More Internet Clever... - Donegal Daily

Letterkenny has been urged to become more ?online? savvy so that local businesses can more money from the internet.

Fine Gael councillor Jimmy Kavanagh said that some businesses are actively engaging and selling their services and products online but others aren?t.

He has now tabled a motion for the latest meeting of Letterkenny Town Council asking that ?the council liaise with the chamber of commerce and other interested parties to devise a strategy for ecommerce for the town.?

Councillor Kavanagh revealed a recent study by Visa Europe showed that Irish consumers are to spend a total of ?420 million online on gifts in the run up to Christmas, with an average spend of ?227 per shopper?.

?This shows that there is a huge market for online shopping and I feel that local businesses are not geared to taking advantage of this potential.

?Some traders in the town are actively engaged with internet selling, but they are the exception rather than the rule. We have excellent Donegal and Irish products available and excellent gift and craft shops that are ideal for internet trading.

?With so many Donegal and Irish people now living and working abroad, it is the perfect time for traders to get involved with online markets. Consumer confidence in trading online is now high thanks to; much improved online security, the fact that most people are now very comfortable using the internet, and the easy availability of online access from smartphones and tablets as well as the more traditional laptops and PC?s,? he said.

He added that the availability of cloud computing also means that it is becoming easier and cheaper for traders to add an online dimension to their business.

?I feel that the council has the ability and the know how to bring interested parties together, look at the opportunities and devise a strategy for the town around online trading. LYIT is also producing IT graduates of a very high standard and there is an opportunity for the college to get involved and lend their expertise.

?I feel that a proper strategy on online trading for the town with clear objectives and goals would be a huge help to local business and would create some much needed employment in the Town? Kavanagh concluded.

?

Source: http://www.donegaldaily.com/2012/12/08/businesses-urged-to-get-more-internet-clever-to-make-more-cash/

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Scientists identify genes that predict whether trastuzumab will work for breast cancer patients

ScienceDaily (Dec. 7, 2012) ? Adding the drug trastuzumab to chemotherapy prevents cancer recurrence and improves survival in a large number of women with early stage HER2-positive breast cancer. But trastuzumab does not stop tumors from returning in about 25 percent of patients -- and oncologists haven't been able to identify these women before treatment. This situation may soon change, according to a Mayo Clinic study being presented at the 2012 CTRC-AACR San Antonio Breast Cancer Symposium.

A team of U.S. researchers, led by oncologists at Mayo Clinic's campus in Florida, have discovered 27 genes that are significantly associated with a good outcome with concurrent use of trastuzumab and chemotherapy, as well as five other genes linked to a poor outcome using the same treatment regimen.

Results of their study -- believed to be the first to use gene expression profiling to predict outcome to trastuzumab as part of adjuvant breast cancer therapy -- offer a number of future potential benefits, says Edith Perez, M.D., deputy director at large of the Mayo Clinic Comprehensive Cancer Center and director of the Breast Cancer Translational Genomics Program at Mayo Clinic.

"These findings also are getting us closer to unraveling the biological factors that are relevant to patient outcome, which will help us improve clinical care," Dr. Perez says.

For example, the discovery may help scientists devise a genetic test that can help oncologists select the best treatment for their HER2-positive patients, she says.

Further analysis will illuminate the inner biological workings of individual HER2-positive tumors, which could provide clues for novel treatments, Dr. Perez adds. The researchers have already found that the genes linked to outcome can be grouped into different categories that affect tumor functioning, such as cell cycle, cell death, cell receptor signaling, and gene transcription.

Dr. Perez and her team plan to validate their findings through collaborations with researchers in the United States and Europe who have led other trastuzumab clinical studies.

"We are on our way to developing a predictive test that can define the right treatment for individual patients, and that is very exciting," she says.

The study was funded by grants from the National Cancer Institute and Mayo Clinic, with further support from the Breast Cancer Research Foundation and the 26.2 with Donna Foundation. The N9831 clinical trial was conducted by the North Central Cancer Treatment Group, now part of the Alliance for Clinical Trials in Oncology. Dr. Perez is a group vice chair for the Alliance.

The study's co-authors include researchers from Mayo Clinic's campuses in Florida, Minnesota and Arizona, Indiana University, Dana-Farber Cancer Institute, the University of Washington, and Ventana Medical Systems-Roche in Tucson, Ariz.

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Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/rSn8xIBvy1A/121207225026.htm

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Rare Beijing protest takes aim at high speed rail project

BEIJING (Reuters) - Authorities in Beijing allowed a rare protest to take place on Sunday against a new high speed rail line, with about 300 demonstrators shouting slogans disrupting traffic in a busy eastern suburb.

Residents told Reuters they were concerned the new line from Beijing to the northeastern city of Shenyang would run too close to their apartments and local schools, causing excess noise and electromagnetic radiation.

They also complained the government had refused to listen to their concerns and accused them of faking an environmental impact assessment.

"I only knew this line was planned two weeks ago when I got a letter from the government thanking me for my support," said a protester who gave her family name as Zhang. "But neither me nor any of the other residents support this. They are inventing things."

Reuters was unable to reach government officials to seek comment.

Police allowed the largely middle-class protesters to march down a main road, where they briefly blocked an intersection shouting "down with the high speed line" and "change the route".

They peacefully dispersed later in the afternoon.

The stability-obsessed ruling Communist Party is wary of any protests, especially in the sensitive capital of Beijing, and often detain demonstrators or break up protests before they reach critical mass.

The party worries that the tens of thousands of sporadic protests over land grabs, corruption, environmental problems and economic grievances that break out every year could coalesce into a national movement and threaten its control.

In 2008, hundreds of people in China's financial hub Shanghai marched against the extension of the city's magnetic levitation train, or "maglev", worried it would emit radiation and sicken them. Police detained dozens.

(Reporting by Ben Blanchard; Editing by Jeremy Laurence)

Source: http://news.yahoo.com/rare-beijing-protest-takes-aim-high-speed-rail-091700188.html

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T-Mobile confirms trials for GoSmart Mobile prepaid, may take it US-wide in 2013

TMobile confirms trial runs for prepaid GoSmart Mobile network, may go nationwide in 2013

Despite T-Mobile USA being very comfortable with prepaid service, it hasn't jumped in with both feet like its potential partner MetroPCS or its arch-rival Sprint. The company has just confirmed to FierceWireless that it's not waiting for a merger to experiment further; it's currently trialing GoSmart Mobile, a prepaid-only network that uses data speed, not caps, as the incentive to jump to higher tiers. Paying $30 per month offers unlimited calling and texting with no internet access whatsoever, while $35 a month includes unlimited 2G data and $45 upgrades to 3G. While that's not as good a deal for data as Virgin Mobile, it's better for those who truly prefer unlimited voice. The carrier hasn't said how it would balance the new service with its MetroPCS, but it has some time to sort this out when any possible nationwide launch won't take place until 2013.

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Via: FierceWireless

Source: GoSmart Mobile

Source: http://www.engadget.com/2012/12/07/t-mobile-confirms-trial-runs-for-prepaid-gosmart-mobile-network/

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Saturday, December 8, 2012

Rotting whale casts foul stench into Malibu

A woman walks her dog past a dead young male fin whale that washed up Monday between the Paradise Cove and Point Dume areas of Malibu, Calif. on Thursday, Dec. 6, 2012. The rotting carcass near celebrity homes is causing a gigantic cleanup problem as authorities try to decide who's responsible for getting rid of it. Los Angeles County lifeguards planned to try to pull the 40,000-pound carcass out to sea, perhaps at high tide Thursday, said Cindy Reyes, executive director of the California Wildlife Center.( AP Photo/Nick Ut)

A woman walks her dog past a dead young male fin whale that washed up Monday between the Paradise Cove and Point Dume areas of Malibu, Calif. on Thursday, Dec. 6, 2012. The rotting carcass near celebrity homes is causing a gigantic cleanup problem as authorities try to decide who's responsible for getting rid of it. Los Angeles County lifeguards planned to try to pull the 40,000-pound carcass out to sea, perhaps at high tide Thursday, said Cindy Reyes, executive director of the California Wildlife Center.( AP Photo/Nick Ut)

People look at a dead young male fin whale that washed up Monday between the Paradise Cove and Point Dume areas of Malibu, Calif. on Thursday, Dec. 6, 2012. The rotting carcass near celebrity homes is causing a gigantic cleanup problem as authorities try to decide who's responsible for getting rid of it. Los Angeles County lifeguards planned to try to pull the 40,000-pound carcass out to sea, perhaps at high tide Thursday, said Cindy Reyes, executive director of the California Wildlife Center.( AP Photo/Nick Ut)

Sea birds pick at the carcass of a young male fin whale that washed up Monday between the Paradise Cove and Point Dume areas of Malibu, Calif. on Thursday, Dec. 6, 2012. The rotting carcass near celebrity homes is causing a gigantic cleanup problem as authorities try to decide who's responsible for getting rid of it. Los Angeles County lifeguards planned to try to pull the 40,000-pound carcass out to sea, perhaps at high tide Thursday, said Cindy Reyes, executive director of the California Wildlife Center.( AP Photo/Nick Ut)

People look at a dead young male fin whale that washed up Monday between the Paradise Cove and Point Dume areas of Malibu, Calif. on Thursday, Dec. 6, 2012. The rotting carcass near celebrity homes is causing a gigantic cleanup problem as authorities try to decide who's responsible for getting rid of it. Los Angeles County lifeguards planned to try to pull the 40,000-pound carcass out to sea, perhaps at high tide Thursday, said Cindy Reyes, executive director of the California Wildlife Center. (AP Photo/Nick Ut)

(AP) ? A dead whale rotting near the Malibu homes of Barbra Streisand, Bob Dylan and other celebrities is causing a gigantic cleanup problem as authorities try to decide who's responsible for getting rid of it.

Los Angeles County lifeguards planned to try to pull the 40,000-pound carcass out to sea at high tide, said Cindy Reyes, executive director of the California Wildlife Center.

But fire Inspector Brian Riley said that's unlikely to work.

"You would need a tug boat to drag it out to sea," Riley told City News Service in a report Thursday.

"It is entrenched in the sand and impossible to tow free even at high tide," Riley said. "Burial at low tide will be difficult as well as land removal. It's in an area with bad access."

The city was not sure who would do the job, spokeswoman Olivia Damavandi said.

The Los Angeles County Department of Beaches and Harbors was not responsible for disposing of the more than 40-foot body, said Carol Baker, who represents the agency.

"It's on a private beach" controlled by homeowners down to the high tide line and the state is responsible for the tidelands, Baker said.

The young male fin whale washed up Monday between Paradise Cove and Point Dume, near the homes of the rich and famous, including Streisand and Bob Dylan.

The whale may have been hit by a ship and had a gash to its back and a damaged spine, according to results of a necropsy conducted Tuesday by the wildlife center.

"It's relatively common for it to happen. It's really unfortunate," Reyes told the Los Angeles Times (http://lat.ms/UGcue1 ).

Such accidents have become more common as increased numbers of migrating blue, fin and humpback whales swim to California's shore to feast on shrimp-like krill.

Fin whales are endangered and about 2,300 live along the West Coast. They're the second-largest species of whale after blue whales and can grow up to 85 feet, weigh up to 80 tons and live to be 90 years old.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2012-12-07-Dead%20Whale/id-13ae510cd32c4a70ad564960285d2da3

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Vaginal microbicide gel may offer a promising strategy for prevention and protection against HIV transmission

ScienceDaily (Dec. 6, 2012) ? A new study shows that a microbicide gel is highly effective in block infection by the AIDS virus in a non-human primate model. In the paper published December 6 in the Open Access journal PLOS Pathogens, Dereuddre-Bosquet and colleagues from the European Combined Highly Active Anti-Retroviral Microbicides (CHAARM) Consortium describe the gel's key ingredient, which are small peptides engineered to present a decoy to bind up the virus and prevent it from entering and infecting the cells of the body. Because this is a gel it can be topically applied and could represent a powerful preventative agent against sexual transmission of HIV.

Worldwide, the scientific community is working on the development of a vaccine against HIV. Meanwhile, research is also focused on the reduction of the spread of the virus by the application of a microbicide gel to protect users during intercourse which is a time of first exposure to virus. To date, few treatments that block virus entry have shown promising protection.

Dereuddre-Bosquet et al. engineered peptides named "miniCD4s" because they mimic the CD4 receptor used by HIV to gain entry into immune cells of the body. The study shows that the miniCD4s blocks HIV entry into isolated cells in a dish and tissue models that mimic mucous membranes which are points of virus entry. The authors then formulated miniCD4s at 0.3% in a microbicide gel that was vaginally applied to six female cynomolgus macaques monkeys for one hour before the animals were given a high dose of the virus also in the vagina. This dose would ordinarily make the animals highly infection but instead, five of the six were completely protected from HIV infection. No trace of virus was found in any body tissue. They were also unable to detect any antibodies to the virus in the plasma of the animals, indicating that the virus was completely repelled and there was full protection.

This study provides a proof of principle that for a a promising strategy for the prevention and protection against HIV ransmission during sexual intercourse. Importantly, the protection was demonstrated in a non human primate model which represents an essential step prior needed to progress to a prospective clinical trial.

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Journal Reference:

  1. Nathalie Dereuddre-Bosquet, Laurence Morellato-Castillo, Joachim Brouwers, Patrick Augustijns, Kawthar Bouchemal, Gilles Ponchel, Oscar H. P. Ramos, Carolina Herrera, Martha Stefanidou, Robin Shattock, Leo Heyndrickx, Guido Vanham, Pascal Kessler, Roger Le Grand, Lo?c Martin. MiniCD4 Microbicide Prevents HIV Infection of Human Mucosal Explants and Vaginal Transmission of SHIV162P3 in Cynomolgus Macaques. PLoS Pathogens, 2012; 8 (12): e1003071 DOI: 10.1371/journal.ppat.1003071

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/Lbrs7QyKMO4/121206203242.htm

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High hormone levels put young black males at risk for cardiovascular disease

High hormone levels put young black males at risk for cardiovascular disease [ Back to EurekAlert! ] Public release date: 7-Dec-2012
[ | E-mail | Share Share ]

Contact: Toni Baker
tbaker@georgiahealth.edu
706-721-4421
Georgia Health Sciences University

AUGUSTA, Ga. Increased levels of the hormone aldosterone in young black males correlate with an unhealthy chain of events that starts with retaining too much salt and results in an enlarged heart muscle, researchers say.

The findings indicate physicians may want to reach for aldosterone inhibitors early in their effort to control blood pressure and reduce cardiovascular risk in young black males.

Their studies of a cohort of 191 healthy black and white 15- to 19-year-olds showed that only in the black males was higher aldosterone associated with impaired sodium excretion, increased blood pressure and enlargement of the left pumping chamber of the heart, said Dr. Gregory A. Harshfield, hypertension researcher at the Medical College of Georgia and Institute of Public and Preventive Health at Georgia Health Sciences University.

"It's a clear pathway and is consistent with the idea that is the highest risk group for developing earlier and more severe cases of hypertension," Harshfield said. Increased sodium makes the body hold onto more fluid, which increases blood pressure. Unhealthy enlargement of the pumping chamber of the heart, called left ventricular hypertrophy, results from the heart having to work too hard against high blood pressures to push blood and oxygen out to the body. Harshfield's studies have shown that black males particularly have a problem with blood pressure returning to normal following stress because of an impaired ability to eliminate sodium.

"It might be a good idea to consider early on drugs that target aldosterone in these individuals," said Diana G. Murro, a fourth-year student at MCG and first author of the study in the journal Pediatric Nephrology. While aldosterone inhibitors are used to treat refractory hypertension, they typically are not used in blacks, possibly because they haven't been well studied in that population, Harshfield said.

The steroid hormone aldosterone, produced by the adrenal gland, is part of a renin-angiotensin-aldosterone system that helps the body regulate blood pressure and sodium retention. Aldosterone acts on the kidneys, prompting them to hold onto sodium which increases blood pressure. While that can be an asset in some finite scenarios, such as having limited access to water over an extended period, it can become a major health liability in the everyday world where you can consume a day's sodium requirement in single pack of crackers, Murro said.

Each of the other subgroups of young, healthy individuals actually showed some negative impact from higher aldosterone. In white and black females, it correlated with higher baseline blood pressures. In fact, white females had the highest aldosterone levels. In white males, it correlated with reduced sodium excretion. "It was more like we had a piece of the puzzle but not the whole puzzle like we did in the black males," Murro said.

Still, all the findings were concerning, Harshfield said. "This is a normal, healthy group of young people and we are already seeing these associations."

Interestingly, only 16 of the study participants were obese, and there was no significant correlation between obesity a major contributor to hypertension and heart disease and higher aldosterone.

Similar studies are needed in hypertensive youth or those with a family history of high blood pressure to see if their findings hold, the researchers said. One of the newer, more selective aldosterone blockers, eplerenone, has proven more effective than the angiotensin II receptor blocker losartan at treating hypertension in a predominantly black, adult male population. While angiotensin is a precursor for aldosterone, at least one study indicates it's not very effective at directly suppressing aldosterone.

Fewer than half of hypertensive Americans have their blood pressure under control, according to the Centers for Disease Control and Prevention. The MCG research was funded by the National Institutes of Health. Murro worked with Harshfield as a member of the inaugural GHSU Child Health Discovery Institute Summer Scholars Program.

###



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High hormone levels put young black males at risk for cardiovascular disease [ Back to EurekAlert! ] Public release date: 7-Dec-2012
[ | E-mail | Share Share ]

Contact: Toni Baker
tbaker@georgiahealth.edu
706-721-4421
Georgia Health Sciences University

AUGUSTA, Ga. Increased levels of the hormone aldosterone in young black males correlate with an unhealthy chain of events that starts with retaining too much salt and results in an enlarged heart muscle, researchers say.

The findings indicate physicians may want to reach for aldosterone inhibitors early in their effort to control blood pressure and reduce cardiovascular risk in young black males.

Their studies of a cohort of 191 healthy black and white 15- to 19-year-olds showed that only in the black males was higher aldosterone associated with impaired sodium excretion, increased blood pressure and enlargement of the left pumping chamber of the heart, said Dr. Gregory A. Harshfield, hypertension researcher at the Medical College of Georgia and Institute of Public and Preventive Health at Georgia Health Sciences University.

"It's a clear pathway and is consistent with the idea that is the highest risk group for developing earlier and more severe cases of hypertension," Harshfield said. Increased sodium makes the body hold onto more fluid, which increases blood pressure. Unhealthy enlargement of the pumping chamber of the heart, called left ventricular hypertrophy, results from the heart having to work too hard against high blood pressures to push blood and oxygen out to the body. Harshfield's studies have shown that black males particularly have a problem with blood pressure returning to normal following stress because of an impaired ability to eliminate sodium.

"It might be a good idea to consider early on drugs that target aldosterone in these individuals," said Diana G. Murro, a fourth-year student at MCG and first author of the study in the journal Pediatric Nephrology. While aldosterone inhibitors are used to treat refractory hypertension, they typically are not used in blacks, possibly because they haven't been well studied in that population, Harshfield said.

The steroid hormone aldosterone, produced by the adrenal gland, is part of a renin-angiotensin-aldosterone system that helps the body regulate blood pressure and sodium retention. Aldosterone acts on the kidneys, prompting them to hold onto sodium which increases blood pressure. While that can be an asset in some finite scenarios, such as having limited access to water over an extended period, it can become a major health liability in the everyday world where you can consume a day's sodium requirement in single pack of crackers, Murro said.

Each of the other subgroups of young, healthy individuals actually showed some negative impact from higher aldosterone. In white and black females, it correlated with higher baseline blood pressures. In fact, white females had the highest aldosterone levels. In white males, it correlated with reduced sodium excretion. "It was more like we had a piece of the puzzle but not the whole puzzle like we did in the black males," Murro said.

Still, all the findings were concerning, Harshfield said. "This is a normal, healthy group of young people and we are already seeing these associations."

Interestingly, only 16 of the study participants were obese, and there was no significant correlation between obesity a major contributor to hypertension and heart disease and higher aldosterone.

Similar studies are needed in hypertensive youth or those with a family history of high blood pressure to see if their findings hold, the researchers said. One of the newer, more selective aldosterone blockers, eplerenone, has proven more effective than the angiotensin II receptor blocker losartan at treating hypertension in a predominantly black, adult male population. While angiotensin is a precursor for aldosterone, at least one study indicates it's not very effective at directly suppressing aldosterone.

Fewer than half of hypertensive Americans have their blood pressure under control, according to the Centers for Disease Control and Prevention. The MCG research was funded by the National Institutes of Health. Murro worked with Harshfield as a member of the inaugural GHSU Child Health Discovery Institute Summer Scholars Program.

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Source: http://www.eurekalert.org/pub_releases/2012-12/ghsu-hhl120712.php

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Friday, December 7, 2012

No Grammy love for Justin Bieber, One Direction

LOS ANGELES (Reuters) - Irate fans of Justin Bieber and boy band One Direction took to social media on Thursday to voice their outrage after being snubbed by the Grammys for a chance to win the biggest honors in the music industry.

Indie-pop band fun and rapper Frank Ocean led the 2013 nominations, tying with The Black Keys, Mumford & Sons, Jay-Z and Kanye West for six nods. But The Recording Academy overlooked some of the year's biggest and most commercially successful artists in Wednesday's nominations.

While Bieber, 18, who won three American Music Awards in November, stayed quiet on his omission, his manager Scooter Braun took to Twitter.

"Grammy board u blew it on this one. the hardest thing to do is transition, keep the train moving. The kid delivered. Huge successful album, sold out tour, and won people over. ... This time he deserved to be recognized," Braun posted in a series of tweets.

Many of Bieber's 31 million Twitter fans quickly followed suit, with hashtags such as #BieberForGrammys trending on the micro-blogging service.

The Canadian singer, who has never won a Grammy, in June released album "Believe," showcasing a more grown-up image. The album, which produced top 10 hits "Boyfriend" and "As Long As You Love Me," has sold more than 1.1 million copies.

British boy band One Direction was also left empty-handed despite their debut album "Up All Night" having topped the Billboard 200 album chart.

The quintet has performed sold-out shows across the world and won three MTV video music awards earlier this year.

The Grammy Awards are voted on by members of The Recording Academy and recognize achievement in 81 categories.

Lady Gaga, rapper Nicki Minaj and Korea's Psy also failed to snag any nominations.

While Gaga hasn't released new music this year, focusing on her global tour, Minaj released "Pink Friday: Roman Reloaded," which topped the Billboard 200 chart and spawned singles such as "Starships."

Psy may have YouTube's most watched video ever with "Gangnam Style," - over 897 million views - but he missed out on becoming the first Korean artist to receive a Grammy nod.

The Grammy Awards will be handed out at a live performance show and ceremony on February 10 in Los Angeles.

(Reporting By Piya Sinha-Roy; editing by Jill Serjeant and Todd Eastham)

Source: http://news.yahoo.com/no-grammy-love-justin-bieber-one-direction-005542568.html

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Exclusive: New Pakistan Taliban chief emerging, will focus on Afghan fight

WANA, Pakistan (Reuters) - Pakistan's Taliban, one of the world's most feared militant groups, are preparing for a leadership change that could mean less violence against the state but more attacks against U.S.-led forces in Afghanistan, Pakistani military sources said.

Hakimullah Mehsud, a ruthless commander who has led the Tehreek-e-Taliban Pakistan (TTP) for the last three years, has lost operational control of the movement and the trust of his fighters, said a senior Pakistan army official based in the South Waziristan tribal region, the group's stronghold.

The organization's more moderate deputy leader, Wali-ur-Rehman, 40, is poised to succeed Mehsud, whose extreme violence has alienated enough of his fighters to significantly weaken him, the military sources told Reuters.

"Rehman is fast emerging as a consensus candidate to formally replace Hakimullah," said the army official, who declined to be identified because of the sensitivity of the matter. "Now we may see the brutal commander replaced by a more pragmatic one for whom reconciliation with the Pakistani government has become a priority."

The TTP, known as the Pakistan Taliban, was set up as an umbrella group of militants in 2007.

Its main aim is to topple the U.S.-backed government in Pakistan and impose its austere brand of Islam across the country of 185 million people, although it has also carried out attacks in neighboring Afghanistan.

The militants intensified their battle against the Pakistani state after an army raid on Islamabad's Red Mosque in 2007, which had been seized by allies of the group.

Mehsud, believed to be in his mid-30s, took over the Pakistan Taliban in August 2009. He rose to prominence in 2010 when U.S. prosecutors charged him with involvement in an attack that killed seven CIA employees at a U.S. base in Afghanistan. His profile was raised further when he appeared in a farewell video with the Jordanian suicide bomber who killed the employees.

Reuters interviewed several senior Pakistan military officials as well as tribal elders and locals during a three-day trip with the army in South Waziristan last week, getting rare access to an area that has been a virtual no-go zone for journalists since an army offensive was launched in October 2009.

Three senior military officials said informers in the Pakistan Taliban told them Mehsud was no longer steering the group.

Pakistan Taliban commanders did not respond to repeated requests for comment on the possible leadership change.

U.S. officials said that while Rehman was Mehsud's natural successor, they cautioned about expecting an imminent transition. Mehsud's standing in the Pakistan Taliban might have weakened, but he still had followers, they said.

Washington has offered a reward of $5 million for information leading to the capture of either Mehsud or Rehman.

One Pakistan military official, who has served in South Waziristan for more than two years, said his Pakistan Taliban contacts first alerted him to Mehsud's waning power six months ago, when constant pressure from the Pakistan military, U.S. drone strikes and poor health had hurt his ability to lead.

"Representing the moderate point of view, there is a probability that under Rehman, TTP will dial down its fight against the Pakistani state, unlike Hakimullah who believes in wanton destruction here," said the military official based in the South Waziristani capital of Wana.

The official said this might lead to more attacks across the border in Afghanistan because Rehman has been pushing for the group's fighters to turn their guns on Western forces.

Other factions within the Pakistan Taliban such as the Nazir group in South Waziristan and the Hekmat Gul Bahadur faction in North Waziristan have struck peace deals with the Pakistani military while focusing attacks on Western and Afghan forces in Afghanistan.

A change in the Pakistan Taliban's focus would complicate Western efforts to stabilize Afghanistan before most NATO troops leave by the end of 2014, said Riaz Mohammad Khan, a Pakistani diplomat who has held several posts dealing with Afghanistan.

The United States is already fighting the Afghan Taliban and the Haqqani network, which is based along the unruly frontier between Afghanistan and Pakistan and which is perhaps Washington's deadliest foe in Afghanistan.

The last thing U.S.-led NATO troops need is a new, formidable enemy in the approach to 2014.

Such a shift in emphasis, however, could reduce the number of suicide bombings that have plagued Pakistan in recent years, scaring off investment needed to prop up an economy that has barely managed to grow since 2007.

AT EACH OTHER'S THROATS

The Pakistan Taliban, who are close to al Qaeda, remain resilient despite a series of military offensives. They took part in a number of high-profile operations, including an attack on army headquarters in 2009, assaults on military bases, and the attempted assassination of Pakistani schoolgirl Malala Yousufzai in October, who had campaigned for girls' education.

The Pakistan Taliban were also blamed for the 2008 bombing of the Marriott Hotel in Islamabad which killed more than 50 people.

Under Mehsud, the organization formed complex alliances with other militant groups spread across Pakistan.

But it has long been strained by internal rivalries over strategy. Mehsud has pushed the war with the Pakistani state, while others such as Rehman want the battle to be against U.S. and allied forces in Afghanistan.

"Rehman has even held secret negotiations with the Pakistani government in the past but Hakimullah always stood in his way, wanting to carry on fighting the Pakistani military," a second Wana-based military official said.

The two were at each other's throats earlier this year and hostilities were close to open warfare, Taliban sources said.

"Differences within the ranks have only gotten worse, not better, rendering the TTP a much weaker force today than a few years ago," the second military official said.

A source close to the Taliban told Reuters there had been months of internal talks on the Pakistan Taliban's decreasing support among locals and fighters in tribal areas where the group has assassinated many pro-government elders.

"The Taliban know they are fighting a public relations war, and under someone like Hakimullah, they will only lose it," added the source, who declined to be identified because he was not authorized to speak to the media.

It isn't clear whether Mehsud will hand over the leadership to Rehman without a fight.

A power struggle could split the group, making it more difficult to recruit young fighters and also disrupt the safe havens in Pakistan used by Afghan militants.

According to accepted practice, a leadership council, or shura, will ultimately decide whether to formally replace Mehsud with Rehman.

Intelligence officials said Mehsud had not commanded any recent operations, including an August 16 attack on the Minhas Airbase in Pakistan and a suicide attack on a street market in May that killed 24 people.

Military sources said Rehman planned the April 15 jail break in Bannu in Pakistan that freed 384 prisoners, including an estimated 200 Taliban members and an al Qaeda-linked militant who had attempted to assassinate former president Pervez Musharraf.

FALL FROM GRACE

Intelligence officials in the area said Mehsud's brutality had turned his own subordinates against him, while the more measured Rehman had emerged as the group's primary military strategist.

"If a leader doesn't behave like a leader, he loses support. For the longest time now, Hakimullah has done the dirty work while Wali-ur-Rehman is the thinker. Taliban fighters recognize this," said the first Pakistani military source.

A local elder described Mehsud as "short-tempered and trigger-happy".

"(Mehsud) used to work 24 hours a day, tirelessly. But he would also put a gun to anyone's head and kill them for his cause," said a local shopkeeper who has family members involved in the Pakistan Taliban.

Mehsud gained his reputation fighting with the Afghan Taliban against U.S. and allied forces in Helmand province in Afghanistan. He was later given command of Taliban factions in the Bajaur, Orakzai, Khyber and Kurram regions.

He took over the Pakistan Taliban after a weeks-long succession battle with Rehman following the death of Baitullah Mehsud in a drone strike. The two Mehsuds were not related.

(Additional reporting by Jibran Ahmad in Peshawar; Editing by Randy Fabi, Michael Georgy and Dean Yates)

Source: http://news.yahoo.com/exclusive-pakistan-taliban-chief-emerging-focus-afghan-fight-103046052.html

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Real Estate App Open Home Pro Expands Beyond Open Houses ...

Open Home Pro, a startup that began as an iPad application allowing realtors to collect info from potential buyers at open houses, is today launching a new app for iPhone. Unlike its big-brother counterpart, the new iPhone application isn?t meant for open houses, but rather for posting new listings online in a matter of minutes.

One Home Pro-1The app takes advantage of the iPhone?s built-in camera and ability to take high-res photos to help flesh out the listing details. After also entering the standard info (address, BR/BA, price, agent info, etc.), realtors can then immediately share the listing on Facebook, send it out as a pre-formatted HTML email, and even post the listing to Craigslist.

Founder Andrew Machado admits he hopes that the latter option won?t be shut down. However, even if so, that may not matter in the long run, as the plan is to eventually work with third parties like Zillow or Trulia, for example, to immediately post listings directly to services that attract buyers? eyeballs.

But in the meantime, Machado describes the new iPhone app as the quickest way to post listings and their accompanying photos online. ?Great photos exist,? he explains, ?it?s just that [realtors] can?t upload them to their local MLSs [multiple listing services] because that technology was built 15 years ago.? There are some 900 MLSs out there, Machado says, and they have a tendency to make photos look worse than they actually are. He refers to MLS?s handling of photos as a ?sausage machine? even, as the photos are crunched down, with a border and watermark added upon upload. ?By the time they leak out to Trulia, they just don?t look that great,? he says.

One Home Pro-2While today?s realtors can?t avoid using MLS entirely, there?s an immediacy that One Home Pro?s iPhone app can provide that would be especially helpful in markets where new listings go quickly. Realtors could be taking calls and booking showings before they or their administrative assistants ever get around to the tedious data entry that is the MLS input process.

The iPhone app also supports realtor profiles, a Twitter-like following model ? which allows all the realtors in an office to quickly network with others ? a favoriting feature, a section featuring trending listings, and more.

As for the iPad version of the application, it has already demonstrated a bit of traction, given the niche market being targeted. The National Association of Realtors currently has 1 million registered members across both residential and commercial markets, for example. Without buying users, with little social integration (until now), and with a fairly high price point ($12 for the iPad app), One Home Pro has grown its install base to 27,000 users since its debut last year.

Today, 15,000 leads flow through its system per month, and the email success rates for the iPad app are at 93 percent. For those unfamiliar, the iPad version allows realtors to email immediately following the open house, again when the price is dropped and, finally, when the home is sold. It also lets realtors export leads into their preferred CRM system, which is often just their iCloud address book.

The iPad and web versions (yep, some realtors are old-school) of the service have both supported photos before today, and 170,000 images have been posted to date. That number will surely grow with today?s launch of the iPhone app. The new app is available for $2.99 and can be downloaded from iTunes here. A future update will add the much-requested support for rentals, too.

Source: http://techcrunch.com/2012/12/06/real-estate-app-one-home-pro-expands-beyond-open-houses-now-lets-realtors-post-listings-from-their-iphone/

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Sean Bean replaces Brendan Fraser in TNT pilot "Legends"

LOS ANGELES (TheWrap.com) - TNT's upcoming pilot "Legends" is getting a Stark makeover.

Sean Bean, who played ill-fated Lord of Winterfell Eddard Stark in HBO's "Game of Thrones," has signed on to replace Brendan Fraser in TNT's upcoming pilot "Legends."

Fraser dropped out of the pilot last month; the show would have marked his first starring turn on a TV series.

Bean will play Martin Odum, a deep-cover operative who has a chameleon-like ability to transform himself into a different person for each mission. The project is based on a book by spy novelist Robert Littell.

"Homeland" duo Howard Gordon and Alexander Cary are executive-producing the pilot, which comes from Fox 21, as are Jeffrey Nachmanoff ("The Day After Tomorrow") and Jonathan Levin ("Charmed").

Deadline first reported news of Bean's "Legends" casting.

Source: http://news.yahoo.com/sean-bean-replaces-brendan-fraser-tnt-pilot-legends-185752956.html

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Archos GamePad now shipping for ?130: Android 4.1, 1.6GHz CPU and a bona fide D-pad

Archos GamePad now shipping for 130 Android 41, 16GHz CPU and a bona fide Dpad

You've waited long enough, haven't you? The low-cost PMP leader has kept the mantra alive with its GamePad, which is now shipping to those interested for £129.99. Put simply, it's a widescreen gaming handheld that runs Android 4.1 (Jelly Bean), replete with a 1.6GHz dual-core processor and Mali 400mp quad-core GPU. There's a 1,024 x 600 resolution touchpanel, physical control buttons and analog sticks, and the whole thing checks in at just 0.3-inches thick. Unfortunately, there's no word on battery life, but even the optimist in us can't predict a number that'd be worthy of boasting about. Hit up the source link to make plans for purchase, or click past the break for the full presser.

Continue reading Archos GamePad now shipping for ?130: Android 4.1, 1.6GHz CPU and a bona fide D-pad

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Source: Archos

Source: http://www.engadget.com/2012/12/06/archos-gamepad-now-shipping-android-gaming-handheld/

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Thursday, December 6, 2012

Gulf oil spill: Oil-dispersing chemicals had little effect on oil surfacing, according to new study

ScienceDaily (Dec. 4, 2012) ? The 2010 blowout of the Macondo well in the waters of the Gulf of Mexico resulted in the region's largest oil spill in U.S. history. As the Deepwater Horizon (DWH) incident unfolded, in an effort to prevent the oil from coming to the surface and reaching coastal and marsh ecosystems, chemical dispersants were injected at the wellhead. These powerful dispersants, typically used to break up oil slicks at the sea surface had never been used in such large quantities and over such a prolonged period of time in the deep ocean.

A new study published in Environmental Science & Technology, led by University of Miami (UM) Rosenstiel School of Marine & Atmospheric Science Associate Professor of Applied Marine Physics Claire Paris, is the first to examine the effects of the use of unprecedented quantities of synthetic dispersants on the distribution of an oil mass in the water column, based on a modeling approach. The team of researchers included UM Rosenstiel School Assistant Scientist Matthieu Le Henaff and Research Associate Professor Villy Kourafalou, UM Center for Computational Science (CCS) Scientist Judith Helgers and Research Associate Professor Ashwanth Srinivasan, Ph.D. Candidate Zachary Aman from Colorado School of Mines, Research Associate Professor Ajit Subramaniam from Lamont Doherty Earth Observatory at Columbia University, and Professor Dong-Ping Wang from the School of Marine and Atmospheric Science of SUNY at Stony Brook. Together they developed and tested models to show that the application of oil-dispersing chemicals had little effect on the oil surfacing in the Gulf of Mexico.

"Deepwater drilling into large, high-pressure reservoirs of oil and gas located far offshore and hundreds of meters below the ocean's surface involves risks for which we were not adequately prepared," said Paris. "As the oil gushed uncontrolled into the Gulf, injection of chemical dispersant into the deep ocean may have had little effect because the oil was coming out with such pressure that it was already dispersed in small droplets. It is impossible to know whether the synthetic dispersant was well mixed with the oil as it was injected. Our models treat both scenarios, and regardless of whether you have the dispersant in the water mixture or not, the amount of oil reaching the sea surface remained relatively unchanged."

The researchers estimated the distribution of oil droplet sizes with and without injection of dispersant at the wellhead. They then applied a novel oil-mass tracking model of the Connectivity Modeling System (CMS) developed shortly after the DWH incident with a RAPID award from the National Science Foundation (NSF) and presented a three-dimensional simulation of the DWH spill showing the unfolding of the disaster to examine the effect the synthetic dispersant may have had on the oil transport in the water column. The model indicated that the dispersant injected at BP's Macondo wellhead was not necessary to break up the oil. The subsea application of dispersant did not have its expected outcome.

"This study is notable because it presents a comprehensive estimate of the Macondo blowout from the microscopic oil-water interface through the macroscopic transport of crude oil." said chemical engineer Aman. The work served as a milestone in assessing the three dimensional transport of oil in the water column.

"Since the beginning of the spill our model accurately predicted the decoupling between the surface and subsea oil transport, and was unique in showing the southwest extension of the deep plume," said physical oceanographer Le Henaff. "Correct assessment of upwelling and downwelling currents for the circulation model created a realistic scenario that we then used to test the effect of the injection of dispersant on the oil partition."

As global deep-sea oil exploration expands, the model will be helpful in quantifying the utility of synthetic dispersants for deep water oil leaks. "The CMS oil model was able to predict the strange layering of oxygen deficit anomalies that we observed during our field sampling and provided us a three dimension view of a phenomena that was constantly changing in time. For us, it was like being able to track the ghosts of the oil plume because the oil itself had been consumed by the microbes and all that was left were the oxygen anomalies and the model was critical for us to understand what we were observing in the field," said biological oceanographer Subramaniam.

These findings expand on a previous study published earlier this year in which the team studied the crucial role of wind-induced surface drift on the fate of the oil in the Gulf of Mexico. "This current study reveals unexplored pathways of the oil transport by underwater currents and highlights the importance of topographic interactions and vertical flows in moving the deep plume toward deep waters or up the water column." said physical oceanographer Wang.

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The above story is reprinted from materials provided by University of Miami Rosenstiel School of Marine & Atmospheric Science, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Claire B. Paris, Matthieu Le H?naff, Zachary M. Aman, Ajit Subramaniam, Judith Helgers, Dong-Ping Wang, Vassiliki H. Kourafalou, Ashwanth Srinivasan. Evolution of the Macondo Well Blowout: Simulating the Effects of the Circulation and Synthetic Dispersants on the Subsea Oil Transport. Environmental Science & Technology, 2012; : 121203084426001 DOI: 10.1021/es303197h

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_environment/~3/30yKeRT4jB4/121204145828.htm

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Wednesday, December 5, 2012

Fungus has cancer-fighting power, researchers find

ScienceDaily (Dec. 4, 2012) ? Arthrobotrys oligospora doesn't live a charmed life; it survives on a diet of roundworm.

But a discovery by a team led by Mingjun Zhang, an associate professor of biomedical engineering at the University of Tennessee, Knoxville, could give the fungus's life more purpose -- as a cancer fighter.

Zhang and his team have discovered that nanoparticles produced by A. oligospora hold promise for stimulating the immune system and killing tumors. The findings are published in this month's edition of Advanced Functional Materials.

Zhang commonly looks to nature for solutions to the world's challenges. He and research associate Yongzhong Wang were examining A. oligospora's trapping mechanism for roundworms when they discovered the fungus secretes nanocomposites consisting of highly uniform nanoparticles. Nanoparticles are tiny particles that have been shown to be important in cancer therapies.

"Naturally occuring nanoparticles have drawn increasing interest from scientific communities for their biocompatibility," said Zhang. "Due to their high surface-to-volume ratio, nanoparticles have demonstrated unique optical, thermal and electronic properties. In addition, their small size allows them to easily cross cell membranes, an essential requirement for cancer therapy."

The researchers investigated the fungal nanoparticles' potential as a stimulant for the immune system, and found through an in vitro study that the nanoparticles activate secretion of an immune-system stimulant within a white blood cell line.

They also investigated the nanoparticles' potential as an antitumor agent by testing in vitro the toxicity to cells using two tumor cell lines, and discovered nanoparticles do kill cancer cells.

According to Zhang, nature faces many diseases, and offers rich mechanisms for curing them as a result of evolution. Nature-based nanostructures possess near endless diversity, which may offer novel solutions for therapeutic applications.

"This study could be the entrance into a gold mine of new materials to treat cancers," said Zhang. "Understanding how these nanostructures are formed in the natural systems will also provide templates for the synthesis of a future generation of engineered nanostructures for biomedical applications."

The researchers' approach promises to open up a new avenue for controlling the synthesis of organic nanoparticles using synthetic biology.

"This exciting discovery is the first step forward in the development of natural nanoparticle-based therapeutics for cancer treatment and demonstrates the importance of looking to nature for innovation in disease treatment," said Zhang.

The research was funded by the Biochemistry Program in the Life Sciences Division of the U.S. Army Research Office.

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The above story is reprinted from materials provided by University of Tennessee.

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Journal Reference:

  1. Yongzhong Wang, Leming Sun, Sijia Yi, Yujian Huang, Scott C. Lenaghan, Mingjun Zhang. Naturally Occurring Nanoparticles fromArthrobotrys oligosporaas a Potential Immunostimulatory and Antitumor Agent. Advanced Functional Materials, 2012; DOI: 10.1002/adfm.201202619

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/strange_science/~3/RA5Dix3vwdI/121204111820.htm

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Say Anything Is North Dakota's Health Insurance Market ...

In a report clearly timed to help make the case for the Obamacare health insurance exchanges (which, I?d remind you readers, would do little to promote competitiveness in the insurance markets), the American Medical Association is claiming that North Dakota?s health insurance market is nearly monopolistic.

That?s the term used by Forum Communications reporter Patrick Springer reporting that Blue Cross Blue Shield of North Dakota owns most of the health insurance market in the state.

FARGO ? North Dakota ranks among the states with near-monopolistic health insurance markets, a study by the American Medical Association shows.

Concentration of health insurance among a handful of firms sets up conditions that lead to higher premium costs and less generous benefits, the study said.

In North Dakota, the private health insurance market has long been dominated by Blue Cross Blue Shield of North Dakota.

Blue Cross Blue Shield dominates the preferred provider segment of the market, in which customers select a health system and have to pay more out of pocket if they go outside that network for care.

The North Dakota Blues have 54 percent of the preferred provider segment, according to the American Medical Association study.

The Blues also have 81 percent of what?s called the point of service market, a hybrid between the preferred provider and more restrictive health maintenance organization, or HMO, which requires a doctor?s authorization for any treatments.

Figures kept by the North Dakota Insurance Department indicate Blue Cross Blue Shield has an even more dominant market position, with about 85 percent of premiums in the standard private health insurance market.

So is the health insurance market in North Dakota a monopoly? First, let?s define what a monopoly is. It is a situation where a single entity owns the entirety of a market, keeping competitors out, for the purpose of inflating prices.

Are those things true in North Dakota? Well, the price part isn?t. North Dakota health insurance prices are below national average even the company ranks in the top tiers for benefits paid:

He said the average 2011 employee contribution for single coverage in North Dakota provided through an employer was $987 in North Dakota, compared to a U.S. average of $1,090, according to figures from Kaiser Family Foundation.

Also, Wagner said, Blue Cross Blue Shield of North Dakota health plans typically are ranked in the top 10 percent to 25 percent in terms of benefit offerings. ?The level of benefits is very high,? he said.

Prices don?t seem to be inflated here (at least not any more than they are in every other part of the country). So how about entry into North Dakota?s insurance marketplace? Unfortunately, North Dakota (like a lot of other states) controls rates and other aspects of the health insurance market through the State Insurance Department. That sort of restrictive regulation always tamps down competition. Price controls and other red tape market it harder for companies to compete with one another in the margins.

So yes, North Dakota has an effective health insurance market, but that?s not the fault of Blue Cross Blue Shield or anyone else in the private sector. That?s the result of restrictive state policies which actively work against competition. Policies that are just going to get worse under Obamacare despite the insurance exchanges which are the federal government?s attempt to manufacture a market that could exist if only we?d embrace deregulation of the insurance industry.

Tags: Adam Hamm, blue cross blue shield, health insurance exchanges, North Dakota News, obamacare

Source: http://sayanythingblog.com/entry/is-north-dakotas-health-insurance-market-monopolistic/

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